Enhanced Na+-K+-activated adenosine triphosphatase activity in transformed fibroblasts.
نویسندگان
چکیده
tase was assayed in various lines of normal and transformed mouse and rat fibroblasts maintained in tissue culture. The rapidly growing, spontaneously transformed 3T6 and 3T12 cells derjved from mouse 3T3 fibroblasts, as well as 3T3 cells transformed by SV40 and murine sarcoma-murine leukemia viruses and XC cells, a line established from a Wistar rat tumor induced with Rous sarcoma, showed a 4to 5-fold greater activity than the normal nontransformed 3T3 Swiss and 3T3 BALB/c clone A31 cell lines. Of the total adenosine triphosphatase activity, 20 to 25% repre sented Na+-K +-activated adenosine triphosphatase in trans
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عنوان ژورنال:
- Cancer research
دوره 34 8 شماره
صفحات -
تاریخ انتشار 1974